Journal: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Article Title: Impact of the Introduction of a Package of Diagnostic Tools, Diagnostic Algorithm, and Training and Communication on Outpatient Acute Fever Case Management at 3 Diverse Sites in Uganda: Results of a Randomized Controlled Trial

doi: 10.1093/cid/ciad341

Figure Lengend Snippet: Diagnostic and treatment algorithm for the intervention arm of a randomized controlled trial that introduced point-of-care diagnostic tests to guide the management of outpatients with febrile illness in Uganda. ‡ Unless a concomitant bacterial pathogen identified. § Start treatment followed by culture if needed. ¶ And neutrophils >75% if WBC >11 000 and/or neutrophils >75% if WBC <11 000. Abbreviations: CBC, complete blood count; CRP, C-reactive protein (mg/L); GAS, group A streptococci; RSV, respiratory syncytial virus; RTI, respiratory tract infection; WBC, white blood cell count (per μL); WHO, World Health Organization.

Article Snippet: Point-of-care tests for the intervention arm included the following: Test-it Typhoid fever IgM rapid test kit (Life Assay Diagnostics); SD Bioline influenza Antigen A/B/A (H1N1) pandemic rapid test kit (Alere/Abbott); Alere BinaxNow respiratory syncytial virus (RSV) card; Streptococcus A test kit (Sekisui OSOM); Streptococcus pneumoniae urine antigen card test (Abbott/Alere); 5-part white blood cell (WBC) differential count POCT (HemoCue); 10-parameter urine test strips (Multistix 10 SG) for leucocyte esterase and nitrites (Siemens); Standard F C-reactive protein (CRP) (SD Biosensor).

Techniques: Diagnostic Assay, Infection, Cell Counting

Journal: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Article Title: Impact of the Introduction of a Package of Diagnostic Tools, Diagnostic Algorithm, and Training and Communication on Outpatient Acute Fever Case Management at 3 Diverse Sites in Uganda: Results of a Randomized Controlled Trial

doi: 10.1093/cid/ciad341

Figure Lengend Snippet: Point-of-Care Tests Performed for Participants in the Intervention Arm of a Randomized Controlled Trial That Introduced Point-of-Care Diagnostic Tests to Guide Management of Outpatients With Febrile Illness at 3 Clinical Sites in Uganda

Article Snippet: Point-of-care tests for the intervention arm included the following: Test-it Typhoid fever IgM rapid test kit (Life Assay Diagnostics); SD Bioline influenza Antigen A/B/A (H1N1) pandemic rapid test kit (Alere/Abbott); Alere BinaxNow respiratory syncytial virus (RSV) card; Streptococcus A test kit (Sekisui OSOM); Streptococcus pneumoniae urine antigen card test (Abbott/Alere); 5-part white blood cell (WBC) differential count POCT (HemoCue); 10-parameter urine test strips (Multistix 10 SG) for leucocyte esterase and nitrites (Siemens); Standard F C-reactive protein (CRP) (SD Biosensor).

Techniques: Diagnostic Assay, Biomarker Assay

Journal: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Article Title: Impact of the Introduction of a Package of Diagnostic Tools, Diagnostic Algorithm, and Training and Communication on Outpatient Acute Fever Case Management at 3 Diverse Sites in Uganda: Results of a Randomized Controlled Trial

doi: 10.1093/cid/ciad341

Figure Lengend Snippet: Bar chart showing the proportion positive of POCTs performed in the intervention arm, over the full study period, in a randomized controlled trial that introduced POCTs to guide the management of outpatients with febrile illness at 3 clinical sites in Uganda. The proportion of each POCT with positive results is shown on the y -axis and months of the year on the x -axis. Abbreviations: POCT, point-of-care test; RDT, rapid diagnostic test.

Article Snippet: Point-of-care tests for the intervention arm included the following: Test-it Typhoid fever IgM rapid test kit (Life Assay Diagnostics); SD Bioline influenza Antigen A/B/A (H1N1) pandemic rapid test kit (Alere/Abbott); Alere BinaxNow respiratory syncytial virus (RSV) card; Streptococcus A test kit (Sekisui OSOM); Streptococcus pneumoniae urine antigen card test (Abbott/Alere); 5-part white blood cell (WBC) differential count POCT (HemoCue); 10-parameter urine test strips (Multistix 10 SG) for leucocyte esterase and nitrites (Siemens); Standard F C-reactive protein (CRP) (SD Biosensor).

Techniques: Diagnostic Assay

Journal: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Article Title: Impact of the Introduction of a Package of Diagnostic Tools, Diagnostic Algorithm, and Training and Communication on Outpatient Acute Fever Case Management at 3 Diverse Sites in Uganda: Results of a Randomized Controlled Trial

doi: 10.1093/cid/ciad341

Figure Lengend Snippet: Pie charts showing the most commonly prescribed antibiotics in a randomized controlled trial that introduced point-of-care tests to guide the management of outpatients with febrile illness at 3 clinical sites in Uganda.

Article Snippet: Point-of-care tests for the intervention arm included the following: Test-it Typhoid fever IgM rapid test kit (Life Assay Diagnostics); SD Bioline influenza Antigen A/B/A (H1N1) pandemic rapid test kit (Alere/Abbott); Alere BinaxNow respiratory syncytial virus (RSV) card; Streptococcus A test kit (Sekisui OSOM); Streptococcus pneumoniae urine antigen card test (Abbott/Alere); 5-part white blood cell (WBC) differential count POCT (HemoCue); 10-parameter urine test strips (Multistix 10 SG) for leucocyte esterase and nitrites (Siemens); Standard F C-reactive protein (CRP) (SD Biosensor).

Techniques: